Spectrum of colonic lesions with cytohistological correlation
Background: Colon is the site of broad array of diseases and is frequently affected by infectious, inflammatory and neoplastic disorders. It is the most common site of gastrointestinal neoplasia in western population. Many benign lesions if not detected in time can progress to malignancy over time. Cancer diagnosis very often results in an enormous change in patient’s psychological well being but at the same time, early diagnosis and prompt treatment plays a very important role in survival of the patient. Flexible colonoscope is well established in procuring histologic and cytologic material for microscopic evaluation. Colonoscopic direct vision brush cytology has several advantages that are not equally possessed by tissue biopsies. Objectives were to study cytomorphological features of colonic lesions, to correlate them with histopathology and evaluate sensitivity and specificity of cytological evaluation.
Methods: In present study, 200 cases of colonic lesions were evaluated cytologically and cytohistopathological correlation was done where possible.
Result: In present study sensitivity of 96.6 % and specificity of 100 % was observed for cytological evaluation.
Conclusion: Brush cytology is a reliable, safe, inexpensive and rapid method of diagnosing gastrointestinal lesions.
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